4 + Resync Collagen Tubs

Red spinach (Botanical name:&nbsp;Amaranthus dubius) is a novel, natural supplement. It contains extremely high levels of vitamin E, iron, and phytoecdysteroids. It increases ventilatory threshold (enhanced breathing and lung capacity) and thus increases the amount of oxygen/air which lungs can hold and utilize efficiently. Additionally, red spinach increases the amount of oxygen to the brain which serves to lower levels of fatigue and stress. Finally, red spinach extract attenuates vascular motility (improves blood flow).&nbsp;<br><br>Oxystorm&nbsp;is one of richest source of standardized natural nitrate extract of red spinach. It has been reported that it&nbsp;delivers the highest nitrate content ingredient from the leaves of red spinach – 9000 mg/100 g – with more than five times the amount of nitrate as beetroot powder and more than 50 times beet juice. It is 100% water soluble, no oxalates or sugar, a unique source of potassium, and has a neutral pH

A relatively new ingredient in the sports market but more clinical studies on Oxystorm are performed every year:<br><br>• Pharmacokinetic studies in healthy adults<br>D. Subramanian, School of Pharmacy, Kerala, India<br><br>• Promotes ventilatory threshold following ingestion of red spinach<br>C.T. Haun, Auburn University, Alabama<br><br>• Sports (Basel)<br>Moore AN et al., 2017 Oct 16;5(4). pii: E80. doi: 10.3390/ sports5040080.<br><br>• Nutrition<br>Subramanian D, Gupta S., 2016 Jul-Aug;32(7-8):748-53. doi: 10.1016/j.nut.2015.12.041..

Aronia berry (chokeberry, Aronia melanocarpa) has been demonstrated to be one of the nature’s one of the most powerful antioxidants. The fruit is valued as a great source of antioxidants, especially polyphenols such as phenolic acids (neochlorogenic and chlorogenic acids). It additionally contains flavonoids (anthocyanins, proanthocyanidins, flavanols and flavonols), particularly cyanidin-3-galactoside and cyanidin-3-arabinoside, as well as (-)-epicatechin units.&nbsp;<br><br>The berries of A. melanocarpa, due to the presence and the high content of these bioactive components, exhibit a wide range of positive effects such as strong antioxidant activity and potential medicinal and therapeutic benefits (gastro-protective, hepato-protective, anti-proliferative or anti-inflammatory activities).

This super berry has been examined in over 200 studies and continues to mesmerize researchers:&nbsp;<br><br>• Effect on inflammatory status in rowers A. Skarpa ska-Stejnborn, University School of Physical Education, Poznań, Poland&nbsp;<br><br>• Modestly lowered blood pressure and reduced low-grade inflammation in subjects B-M. Loo, National Institute of Health, Turku, Finland&nbsp;<br><br>• Positive effect on oxidative damage in triathletes L.A. Garcia-Flores, CEBAS-CSIS, Murcia, Spain&nbsp;<br><br>• Beneficial effects of Aronia on cardiovascular health markers M. Broncel, Medical University of Łódź, Poland&nbsp;<br><br>• Molecules Jurikova T et al., 2017 Jun 7;22(6). pii: E944. doi: 10.3390/molecules22060944.&nbsp;<br><br>• Front Nutrition Banjari I et al., 2017 Nov 6;4:53. doi: 10.3389/fnut.2017.00053.

Hyaluronic acid (HA) is naturally occurring in human body, especially in the eyes and joint fluids. It is a very popular nutraceutical supplement for joint disorders. It is also popular for its application on dermal tissues for wound healing, burns, skin ulcers, and as a moisturizer.<br><br>Basically, in joints, hyaluronic acid acts as a cushion and as a lubricant. However, it plays multifaceted role in regulating various biological processes and maintaining homeostasis in the body. A significant volume of research exhibited the biomedical implications of HA in skin repair, wound healing, tissue regeneration, anti-inflammation, and immunomodulation. A thorough analysis of the literature revealed that HA based formulations (e.g., gels, creams, autologous graft, thin sheets, soaked gauze, gauze pad, tincture, injection) have shown remarkable efficacy in treating a wide range of inflammatory skin diseases.&nbsp;<br><br>The safety, tolerability, and efficacy of HA have also been well-documented for treatment of various types of joint disease including knee osteoarthritis, joint osteoarthritis, canine osteoarthritis, and meniscal swelling. A remarkable improvement in chondrocyte density, territorial matrix appearance, reconstitution of superficial amorphous layer of the cartilage, collagen remodeling, and regeneration of meniscus have also been evident in patients treated with HA. Overall, application/administration of HA is a promising pharmacotherapeutic regimen for treatment of inflammatory skin and joint diseases.

Hyaluronic acid has been used as a joint health promoting ingredients for a while and has been studied in depth:<br><br>• Hyaluronan<br>T.C. Laurent, University of Uppsala, Sweden<br><br>• Evaluation of HA after surgery<br>Bioconti. Prague University, Czech Republic<br><br>• Evaluation of hyaluronic acid in people<br>B. Sardi, Ohtsuma University, Tokyo, Japan<br><br>• Int J Biol Macromol 116<br>Chen LH et al., (2018) 572-584.<br><br>• Clin Transl Med<br>Bowman S et al., 2018 Feb 16;7(1):6. doi: 10.1186/s40169-017-0180-3.<br><br>• Cartilage<br>Altman R et al., 2018 Feb 1:1947603517749919. doi: 10.1177/1947603517749919.<br><br>• J Biol Regul Homeost Agents<br>Papalia R et al., 2017 Dec 27;31(4 Suppl 2):91-102.

Collagen peptides are smaller pieces of collagen that are safe and allergen free. More specifically, hydrolyzed collagen peptides (broken down collagen) are made for better absorption for people interested in strengthening their body via collagen peptide supplements. When collagen goes through hydrolysis (breakdown through water) it becomes much more bioavailable and is more easily absorbed by your body. Fast digestion and rapid absorption can only enhance muscle and connective tissue regeneration.

<br>• Engel, Frank. “WHITEPAPER GROWING FITTER, STRONGER AND HEALTHIER.” Nov. 2018.<br><br>•https://www.naturalproductsinsider.com/sites/naturalproductsinsider.com/files/NPI-WP-Rousselot-1118.pdf</p>
<p><br>• Siebrecht, Stefan, et al. Amazing Collagen Peptides. maudrich publishing house, 2018.

Red Beet (Beta vulgaris) has demonstrated potential benefits in health promoting and disease prevention as a novel functional food. It is a unique source of nitrate, and a promising therapeutic treatment in a range of clinical pathologies associated with free radical injury, oxidative stress, and inflammation.&nbsp;<br><br>Beetroot ingestion provides a natural means of increasing in vivo NO availability and has emerged as a potential strategy to prevent and manage pathologies associated with diminished NO bioavailability, notably hypertension and endothelial function.&nbsp;<br><br>Beetroot contains betalain pigments, displays potent antioxidant, anti-inflammatory and chemo-preventive activities both in vitro and in vivo. Research studies have demonstrated that beetroot supplementation prevents inflammatory responses and oxidative stress, and significantly improves cognitive and endothelial functions.

Many clinical researchers have investigated the benefits of supplementing with beet root:<br><br>• Supplementation with beet root supports enhanced exercise tolerance<br>BC. Breese, Liverpool Hope University, England<br><br>• Inorganic nitrate supplementation supports muscle oxygenation<br>J.B. Bailey, University of Exeter, UK<br><br>• Accelerates postexercise muscle metabolic recovery and O2 delivery<br>A. Vanhatalo, University of Exeter, UK<br><br>• Nitrate Ingestion<br>W.T. Clements, University of Memphis, Tennessee<br><br>• Circ Res<br>Woessner MN et al., 2018 Jul 5. pii: CIRCRESAHA.118.313131. doi: 10.1161/CIRCRESAHA.118.313131.<br><br>• Nutrients 7<br>Clifford T et al, (2015) pp 2801-2822.&nbsp;

"Vitamin C, also known as ascorbic acid, is necessary for the growth, development and repair of all body tissues. It's involved in many body functions, including formation of collagen, absorption of iron, the immune system, wound healing, and the maintenance of cartilage, bones, and teeth. Vitamin C is one of many antioxidants that can protect against damage caused by free radicals, as well as toxic chemicals and pollutants.” Vitamin C may also offer these additional benefits:

• Essential for collagen synthesis
•  Supports healthy immune function†

•   Promotes healthy inflammatory markers†

•  Antioxidant† 

•   Supports healthy skin†

FruiteX-B - Calcium Fructoborate

Calcium fructoborate is a natural source of soluble boron. At the cellular and molecular level, calcium fructoborate has been demonstrated to be superior to the boric acid/borate, exhibiting a complex support against insult.† Calcium fructoborate may provide the following benefits:

 
• Supports joint health†
• Supports joint flexibility†
• Supports healthy inflammatory markers†